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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FOXO4 All Species: 21.82
Human Site: T123 Identified Species: 53.33
UniProt: P98177 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P98177 NP_005929.2 505 53684 T123 S A P E K R L T L A Q I Y E W
Chimpanzee Pan troglodytes XP_001135016 505 53494 T123 S A P E K R L T L A Q I Y E W
Rhesus Macaque Macaca mulatta XP_001088437 860 91177 T387 S S A E K R L T L S Q I Y E W
Dog Lupus familis XP_549066 509 54008 L127 A P E K R L T L A Q I Y E W M
Cat Felis silvestris
Mouse Mus musculus Q9WVH3 505 53631 T123 S A P E K R L T L A Q I Y E W
Rat Rattus norvegicus NP_001100413 505 53925 T123 S A P E K R L T L A Q I Y E W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426261 470 50115 K98 M L N P E G G K S G K A P R R
Frog Xenopus laevis Q6EUW1 657 70366 T164 S T Q D K R L T L S Q I Y D W
Zebra Danio Brachydanio rerio XP_692168 613 64303 K209 I R A K Q T K K Q A G A A G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95V55 613 67394 A213 R V E A L R Q A G V V G L N D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 31.9 92.1 N.A. 88.5 88.3 N.A. N.A. 53.4 37.9 44.2 N.A. 28.5 N.A. N.A. N.A.
Protein Similarity: 100 98.8 42 95 N.A. 93 92.4 N.A. N.A. 63.5 52 56.2 N.A. 43.5 N.A. N.A. N.A.
P-Site Identity: 100 100 80 0 N.A. 100 100 N.A. N.A. 0 66.6 6.6 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 20 N.A. 100 100 N.A. N.A. 13.3 86.6 20 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 40 20 10 0 0 0 10 10 50 0 20 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 10 % D
% Glu: 0 0 20 50 10 0 0 0 0 0 0 0 10 50 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 10 0 10 10 10 10 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 10 60 0 0 10 % I
% Lys: 0 0 0 20 60 0 10 20 0 0 10 0 0 0 0 % K
% Leu: 0 10 0 0 10 10 60 10 60 0 0 0 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 40 10 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 10 0 10 0 10 0 10 10 60 0 0 0 0 % Q
% Arg: 10 10 0 0 10 70 0 0 0 0 0 0 0 10 10 % R
% Ser: 60 10 0 0 0 0 0 0 10 20 0 0 0 0 0 % S
% Thr: 0 10 0 0 0 10 10 60 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 60 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 60 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _